The skin’s ability to regenerate depends on the balance between the production and breakdown of collagen and elastin, the proteins that ensure its firmness, elasticity and resilience. Over time, this balance tends to be disrupted, leading to the appearance of signs of ageing. Genetics also play an important role: variations in genes involved in skin renewal and the synthesis of collagen and elastin can influence the skin’s natural ability to maintain its youthful appearance. Understanding this predisposition helps guide the choice of personalised cosmetic treatments, designed to support the skin’s regenerative processes.

Low-grade chronic inflammation is one of the main mechanisms involved in skin ageing, to the extent that it has been termed ‘inflammaging’. When inflammatory processes persist over time, they contribute to the deterioration of skin structures and accelerate the appearance of wrinkles, loss of elasticity and other signs of ageing. The inflammatory response is also influenced by genetics: variants in specific genes can make it more intense or prolonged. Understanding your own predisposition allows you to choose skincare strategies designed to support the skin’s natural defence mechanisms and help slow down the ageing process.

Oxidative stress is a condition in which the production of reactive oxygen species (ROS) exceeds the body’s ability to neutralise them. This imbalance, driven primarily by exposure to UV rays and other environmental factors, damages DNA, proteins and other cellular structures, accelerating skin ageing and the appearance of wrinkles, dark spots and loss of elasticity. The ability to defend against ROS is also influenced by genetics: variations in the genes involved in antioxidant systems can reduce the efficiency of these mechanisms. Understanding one’s own predisposition allows for the adoption of personalised skincare strategies to protect the skin and preserve its health and beauty for longer.

Photo-ageing is caused by chronic exposure to UV rays, which increases the production of free radicals and accelerates oxidative stress, one of the main causes of skin deterioration. The test assesses a biomarker of mitochondrial DNA damage (Common Deletion, CD), an indicator of the biological impact of sun exposure, and combines this with information on your lifestyle and sun exposure habits. The result is a personalised assessment of skin damage, which is useful for selecting targeted cosmetic and preventative strategies to combat skin ageing.

Personalised genocosmetics transforms genetic information into a personal skincare treatment, tailored to the biological characteristics of your skin. Through DNA analysis, it is possible to identify the key factors involved in the ageing process and skin changes, guiding the selection of active ingredients and formulations that are truly suited to your needs. The result is a personalised skincare regime, based on scientific evidence, which helps to preserve the skin’s physiological balance, optimise the effectiveness of treatments and promote more targeted and long-lasting results.